9606
NCBI
Homo sapiens
10090
NCBI
Mus musculus
10116
NCBI
Rattus norvegicus
WikiUser_17
mammals
Decrease, 11β-Hydroxysteroid dehydrogenase type 2 activity
Decrease, 11β-HSD2 activity
Molecular
Not Specified
Unspecific
Not Specified
Adults
Not Specified
Not Specified
Not Specified
Not Specified
AOPWiki
2026-02-10T06:32:01
2026-02-26T06:53:29
Decreased 11β-Hydroxysteroid dehydrogenase type 2 activity leading to MASLD progression via insulin resistance-associated mitochondrial dysfunction
Decreased 11β-HSD2 leading to MASLD via IR-associated mitochondrial dysfunction
Agnes Aggy
BY-SA
Under Development
2.7
<div>
<table class="table table-bordered table-fullwidth">
<thead>
<tr>
<th>Modulating Factor (MF)</th>
<th>Influence or Outcome</th>
<th>KER(s) involved</th>
</tr>
</thead>
<tbody>
<tr>
<td> </td>
<td> </td>
<td> </td>
</tr>
</tbody>
</table>
</div>
AOPWiki
2026-02-12T09:27:41
2026-06-26T16:12:16