AOPs

OECD View API
Searches both title and fulltext content
Takes you to the requested AOP
Clear Search Terms Clears search terms and filters

Showing 176 to 200 of 548 AOPs

Clear Table Filters
ID Title Point of Contact License MIE AO OECD Status OECD Project
212 Histone deacetylase inhibition leading to testicular atrophy Brendan Ferreri-Hanberry BY-SA 1502: Histone deacetylase inhibition 1506: Testicular atrophy WPHA/WNT Endorsed 1.52
213 Inhibition of fatty acid beta oxidation leading to nonalcoholic steatohepatitis (NASH) Arthur Author Open for adoption 1490: Inhibition, Fatty Acid Beta Oxidation 1489: N/A, Steatohepatisis
214 Network of SSRIs (selective serotonin reuptake inhibitors) Agnes Aggy Open for adoption None
215 Molecular events lead to epilepsy Allie Always Open for adoption None
216 Deposition of energy leading to population decline via DNA strand breaks and follicular atresia Evgeniia Kazymova BY-SA 1686: Deposition of Energy
217 Gastric ulcer formation Cataia Ives Open for adoption None
218 Inhibition of CYP7B activity leads to decreased reproductive success via decreased locomotor activity Brendan Ferreri-Hanberry BY-SA 1386: CYP7B activity, inhibition 360: Decrease, Population growth rate
219 Inhibition of CYP7B activity leads to decreased reproductive success via decreased sexual behavior Arthur Author BY-SA 1386: CYP7B activity, inhibition 360: Decrease, Population growth rate
220 Cyp2E1 Activation Leading to Liver Cancer Agnes Aggy BY-SA 1391: Activation of Cyp2E1 1395: Liver Cancer WPHA/WNT Endorsed 1.24
221 Mental stress to depression Allie Always Open for adoption 1396: Increased, glucocorticoid receptor activity 1346: Increased, depression
222 Mental stress to agitation Evgeniia Kazymova Open for adoption 1396: Increased, glucocorticoid receptor activity 1345: Increased, agitation
223 Serotonin transporter activation to seizure Cataia Ives Open for adoption 1397: Increased, serotonin transporter activity 1344: Increased, seizure
224 Serotonin transporter activation to depression Brendan Ferreri-Hanberry Open for adoption 1397: Increased, serotonin transporter activity 1346: Increased, depression
225 Serotonin transporter activation to agitation Arthur Author Open for adoption None 1345: Increased, agitation
226 SSRI (Selective serotonin reuptake inhibitor) to hypertension Agnes Aggy Open for adoption 1317: Decreased, serotonin transporter activity 1343: Increase, hypertension
227 NSAID induced PTGS1 inactivation to gastric ulcer Allie Always Open for adoption 1402: Reduced, PTGS1 function 1385: Activated, gastric ulcer formation
228 NSAID induced PTGS2 inactivation to gastric ulcer Evgeniia Kazymova Open for adoption 1408: Reduced, PTGS2 function 1385: Activated, gastric ulcer formation
229 Helicobacter pylori to gastric ulcer Cataia Ives Open for adoption 1412: Helicobacter pylori infection 1385: Activated, gastric ulcer formation
230 presynaptic neuron 1 activation to epilepsy Brendan Ferreri-Hanberry Open for adoption 1349: Activated, presynaptic neuron 1 1363: Increased, epilepsy
231 presynaptic neuron 2 repression to epilepsy Arthur Author Open for adoption 1413: Reduced, presynaptic neuron 2 activity 1363: Increased, epilepsy
232 NFE2/Nrf2 repression to steatosis Agnes Aggy Open for adoption 1417: NFE2/Nrf2 repression 459: Increased, Liver Steatosis
233 Mu Opioid Receptor Agonism leading to Analgesia via K Channel Opening Allie Always BY-SA 1425: Mu Opioid Receptor Agonism 1428: Analgesia
234 Mu Opioid Receptor Agonism leading to Analgesia via Ca Channel Inhibition Evgeniia Kazymova BY-SA 1425: Mu Opioid Receptor Agonism 1428: Analgesia
235 Serotonin 1A Receptor Agonism leading to Anti-depressant Activity via K Channel Opening Cataia Ives BY-SA 1431: Serotonin 1A Receptor Agonism 1432: Anti-depressant Activity
236 Serotonin 1A Receptor Agonism leading to Anti-depressant Activity via Ca Channel Inhibition Brendan Ferreri-Hanberry BY-SA 1431: Serotonin 1A Receptor Agonism 1432: Anti-depressant Activity