Key Event Relationships (KERs)

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Showing 1376 to 1400 of 3002 KERs

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ID Upstream Event Downstream Event Creation Date Last Updated AOPs
2748 2054: Increase, impairment of cuticle sclerotization 990: Increase, Incomplete ecdysis Aug 28, 2022 Aug 28, 2022
2749 2055: Increase, pigmentation 990: Increase, Incomplete ecdysis Aug 28, 2022 Aug 28, 2022
2836 2098: Abnormal Neural Remodeling 341: Impairment, Learning and memory Jan 25, 2023 Jul 26, 2024
2091 1768: Increase, Abnormal osmoregulation 1769: Increase, Body fluid overload Apr 30, 2020 Apr 30, 2020
2181 1768: Increase, Abnormal osmoregulation 1809: Increase, Tissue/organ damage Nov 2, 2020 Nov 2, 2020 None
3290 1768: Increase, Abnormal osmoregulation 2238: Increased, Blood viscosity Jul 8, 2024 Dec 3, 2024 None
2736 2045: Increase, Alcohol dehydrogenase 748: Increased, Estrogen receptor (ER) activity Aug 28, 2022 Aug 28, 2022
1487 1384: Increase, ammonium (NH4+) 1382: Decrease, surfactant Apr 17, 2017 Apr 17, 2017
2910 2134: Increase, AR protein expression/abundance 854: Alterations, Cellular proliferation / hyperplasia May 11, 2023 May 11, 2023
1473 1376: Increase, angiogenesis 1367: Inhibit, gastric ulcer formation Apr 17, 2017 Apr 17, 2017
2578 1376: Increase, angiogenesis 1193: N/A, Breast Cancer Feb 15, 2022 Feb 15, 2022 None
3137 1376: Increase, angiogenesis 1982: Metastasis, Breast Cancer Mar 5, 2024 Mar 5, 2024
3308 1376: Increase, angiogenesis 885: Increase, Cancer Jul 18, 2024 Jul 18, 2024 None
1469 1365: Increase, Apoptosis 1366: Decrease, Oogenesis Apr 15, 2017 Apr 15, 2017 None
1596 1365: Increase, Apoptosis 1444: Increase, Follicular atresia Jun 29, 2017 Jun 29, 2017 None
1741 1365: Increase, Apoptosis 1521: Decrease, Growth May 24, 2018 May 24, 2018 None
1751 1365: Increase, Apoptosis 350: Increase, Mortality Jun 12, 2018 Jun 12, 2018
2075 1365: Increase, Apoptosis 1757: Reduce, Sperm count Apr 6, 2020 Apr 6, 2020
2185 1365: Increase, Apoptosis 1809: Increase, Tissue/organ damage Nov 2, 2020 Nov 2, 2020 None
2461 1365: Increase, Apoptosis 759: Increased, Kidney Failure Aug 5, 2021 Aug 5, 2021 None
2602 1365: Increase, Apoptosis 1978: Microcephaly Mar 17, 2022 Mar 17, 2022 None
2619 1365: Increase, Apoptosis 1798: Decreased spermatogenesis Mar 28, 2022 Mar 28, 2022
2645 1365: Increase, Apoptosis 1097: Occurrence, renal proximal tubular necrosis Apr 8, 2022 Apr 8, 2022
2725 1365: Increase, Apoptosis 2041: Decrease, facial prominence outgrowth Jul 28, 2022 Jul 28, 2022 None
2948 1365: Increase, Apoptosis 1430: Inhibition of neurotransmitter release Jun 20, 2023 Jun 20, 2023 None