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Showing 1651 to 1675 of 3002 KERs

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ID Upstream Event Downstream Event Creation Date Last Updated AOPs
1747 1526: Increase, Opening of voltage-dependent calcium channel 1523: Decrease, Cuticular chitin content May 24, 2018 May 24, 2018
2107 1777: Increase, Ovarian follicle breakdown 1366: Decrease, Oogenesis Apr 30, 2020 Apr 30, 2020
2560 1777: Increase, Ovarian follicle breakdown 328: Decrease, Fecundity Feb 4, 2022 Feb 4, 2022 None
2118 1784: Increase, Ovarian follicle breakdown (F3) 1782: Decrease, Oogenesis (F3) Apr 30, 2020 Apr 30, 2020
2106 1776: Increase, Ovarian somatic cell apoptosis 1777: Increase, Ovarian follicle breakdown Apr 30, 2020 Apr 30, 2020
2117 1783: Increase, Ovarian somatic cell apoptosis (F3) 1784: Increase, Ovarian follicle breakdown (F3) Apr 30, 2020 Apr 30, 2020
1909 1634: Increase, Oxidative DNA damage 155: Inadequate DNA repair May 19, 2019 Mar 8, 2024
1913 1634: Increase, Oxidative DNA damage 1635: Increase, DNA strand breaks May 19, 2019 Dec 17, 2024
1914 1634: Increase, Oxidative DNA damage 185: Increase, Mutations May 19, 2019 Jan 9, 2023
2591 1634: Increase, Oxidative DNA damage 1444: Increase, Follicular atresia Mar 1, 2022 Mar 1, 2022
2592 1634: Increase, Oxidative DNA damage 1775: Increase, Oocyte apoptosis Mar 1, 2022 Mar 1, 2022
3230 1634: Increase, Oxidative DNA damage 1461: Increase, DSB May 27, 2024 May 27, 2024
3232 1634: Increase, Oxidative DNA damage 1365: Increase, Apoptosis May 27, 2024 May 27, 2024 None
3359 1634: Increase, Oxidative DNA damage 55: Cell injury/death Oct 8, 2024 Oct 8, 2024 None
3362 1634: Increase, Oxidative DNA damage 1505: Cell cycle, disrupted Oct 8, 2024 Oct 8, 2024 None
3570 1634: Increase, Oxidative DNA damage 1262: Apoptosis Aug 13, 2025 Aug 13, 2025 None
763 769: Increase, Oxidative metabolism 209: Peptide Oxidation Nov 29, 2016 Dec 3, 2016
1362 1279: Increase, Oxidative Stress / Activation, PMK-1 P38 MAPK 1281: Increased, DNA Damage-Repair Feb 15, 2017 Feb 15, 2017
1364 1279: Increase, Oxidative Stress / Activation, PMK-1 P38 MAPK 1280: Activation, HIF-1 Feb 15, 2017 Feb 15, 2017
3166 1279: Increase, Oxidative Stress / Activation, PMK-1 P38 MAPK 177: Mitochondrial dysfunction Mar 14, 2024 Mar 14, 2024
3512 1279: Increase, Oxidative Stress / Activation, PMK-1 P38 MAPK 1115: Increase, ROS Apr 3, 2025 Apr 3, 2025
2340 1865: Increase, OEC damage 1862: Decrease, Photosystem II efficiency Apr 11, 2021 Apr 11, 2021
3552 2337: Increase, PLIN2 2333: Increase, Fat mass Jul 25, 2025 Jul 25, 2025
1241 1173: Increase, Peroxisomal Fatty Acid Beta Oxidation of Fatty Acids 209: Peptide Oxidation Nov 29, 2016 Dec 3, 2016 None
1230 1170: Increase, Phenotypic enzyme activity 716: Increase, cell proliferation (hepatocytes) Nov 29, 2016 Dec 31, 2020