Key Event Relationships (KERs)

API

Fulltext search has been disabled for Key Event Relationships (KERs) at this time. If you need this feature, send an email to aopwiki@googlegroups.com

Queries Key Event Relationship (KER) titles
Filter by Upstream Key Event title
Filter by Downstream Key Event title
Filter by AOP title
Clear All Filters

Showing 1276 to 1300 of 3002 KERs

Clear Table Filters
ID Upstream Event Downstream Event Creation Date Last Updated AOPs
3191 2107: Hypomyelination 2108: Altered, white brain matter Apr 12, 2024 Apr 12, 2024
2197 1819: IFNγ signaling 1633: Increase in inflammation Nov 2, 2020 Nov 2, 2020
2318 1856: Sodium inhibition, Sweet enhancement 1849: Impaired gustatory nerve Apr 10, 2021 Apr 10, 2021
2196 1818: Immune cell activation 1819: IFNγ signaling Nov 2, 2020 Nov 2, 2020
3054 2180: immune mechanisms antagonized 2192: IAV production increased Oct 3, 2023 Oct 3, 2023
1278 1225: Leukocyte infiltration 1226: Respiratory irritability Nov 29, 2016 Dec 3, 2016 None
1290 1225: Leukocyte infiltration 1237: Sensitization, Immune system Nov 29, 2016 Dec 3, 2016 None
1923 1644: Impaired Ab production 986: Impairment of TDAR May 23, 2019 Jun 25, 2019 None
1820 1568: Impaired antigen presentation 1569: Impaired T cell activation Dec 25, 2018 Dec 25, 2018 None
3665 2378: Impaired axonal insulation 386: Neuronal network function, Decreased Oct 8, 2025 Oct 8, 2025
1835 1582: Impaired axonial transport 1583: Sensory axonal peripheral neuropathy Jan 29, 2019 Jan 29, 2019
2506 1582: Impaired axonial transport 1944: Dysfunctional synapses Oct 26, 2021 Oct 26, 2021
2012 1705: Impaired coordination and movement 351: Increased Mortality Dec 20, 2019 Dec 20, 2019
2015 1705: Impaired coordination and movement 360: Decrease, Population growth rate Dec 20, 2019 Dec 20, 2019
3260 364: Impaired development of, Reproductive organs 78: Reduction, Cumulative fecundity and spawning Jul 3, 2024 Jul 3, 2024
2296 1849: Impaired gustatory nerve 1850: taste impairment Mar 28, 2021 Mar 28, 2021
1815 1572: Impaired IL-1 signaling 1565: Suppressed AP-1 Dec 25, 2018 Dec 25, 2018 None
1816 1572: Impaired IL-1 signaling 1566: Suppressed NF-kB Dec 25, 2018 Dec 25, 2018 None
1825 1572: Impaired IL-1 signaling 1573: Suppressed MyD88 Jan 6, 2019 Mar 14, 2019 None
1920 1572: Impaired IL-1 signaling 202: Inhibition, Nuclear factor kappa B (NF-kB) May 23, 2019 Jun 25, 2019 None
2000 1700: Impaired IL-1R1 signaling 1702: Suppression of T cell activation Nov 17, 2019 Nov 17, 2019 None
2002 1700: Impaired IL-1R1 signaling 202: Inhibition, Nuclear factor kappa B (NF-kB) Nov 17, 2019 Sep 29, 2022
1938 1615: Impaired inguinoscrotal phase 1616: Malformation, cryptorchidism Jun 3, 2019 Dec 3, 2024
3179 2144: Impaired insulin signaling 2119: Insulin resistance, increased Apr 9, 2024 Apr 9, 2024
2515 1946: Altered mechanotransduction properties of pericytes 1947: Pericyte dysfunction Oct 28, 2021 Oct 28, 2021 None